Immediately following bolus, the recommended initial infusion rate of diltiazem hydrochloride is 5 mg/hour
Initial dose: 180 to 240 mg orally once a day, increasing the dose as needed 2
25mg/kg with each increase
35 mg/kg or 25 mg over 2 minutes
May adjust infusion rate hereafter from 5-15 mg/hour to maintain HR 70-110 BPM
Consider addition 30mg PO IR Diltiazem q6 hours or home dose to reduce need for drip
Diltiazem affects
As the dose of CARDIZEM tablets is increased from a daily dose of 120 mg (30 mg qid) to 240 mg (60 mg qid) daily, there is an increase in area-under-the-curve of 2
‡Dose should be adjusted for renal function and QT-interval response during in
The infusion rate may be increased in 5 mg/h increments up to 15 mg/h as needed, if further reduction in heart rate is required
25 mg/kg IV bolus over 2 min: 5–10 mg/h: Avoid in hypotension, heart failure, cardiomyopathy, and acute coronary syndromes: Verapamil: 0
Unfractionated heparin may be administered either by continuous intravenous infusion in a dose sufficient to prolong the activated partial thromboplastin time to 1
Infusions of calcium for 24 hours or more may be required
Although dosages may vary based on physician orders, protocols and age, a standard initial dose is 0
Duration of infusion longer than 24 hours and infusion rates greater than 15 mg/h have not been studied For the treatment of angina pectoris, 83
25 mg/kg doses every 5-15 minutes until the desired effect is achieved or side effects appear
Calcium gluconate has also been administered as a continuous infusion at a rate of 2 g per hour for 10 hours
Importantly, these findings are the result of a retrospective study with
The infusion rate may be increased in 5 mg/h increments up to 15 mg/h as needed, if further reduction in heart rate is required, the infusion may be maintained for up to 24 hours
When used as monotherapy, reasonable starting doses are 180 to 240 mg once daily, although some patients may respond to lower doses
25mg/kg with each increase
51: you decide to administer diltiazem
5mg/min until HR <100 or max 50mg; Magnesium Diltiazem 100 mg/100 mL 1 mg/mL Load: 0
Consider a reduction in the infusion rate after the target heart rate is reached